姓 名：毛东海 性 别：男
职 务：
职 称：研究员 学 历：博士
电 话：0731-84619748 通迅地址：湖南省长沙市芙蓉区远大二路644号
传 真：(86)-731-84612685 邮政编码：410125
电子邮件：donghai.mao@isa.ac.cn
研究员，博士，博士生导师，国家高层次人才特殊支持计划青年拔尖，湖南省自然科学基金杰出青年，长沙·中国隆平芯谷青年人才。主要从事水稻产量及其稳定性的遗传基础与分子设计，目前主持国家或省部级课题10余项，在Nat Genet、PNAS、Plant Biotechnol J、Plant Cell Environ、Plant J、Theor Appl Genet、Plant Sci、Mol Breed等国内外期刊发表论文30余篇，申请国家发明专利7项，获湖南省自然科学二等奖1项。
1.国家高层次人才特殊支持计划（青年拔尖）：水稻耐气候逆境基因挖掘与利用，2022-2024，主持；
2.湖南省自然科学基金委（杰出青年）：水稻第11号染色体耐冷QTL簇的基因克隆与协同进化分析，2021-2023，主持；
3.农业农村部科技创新2030重大项目：资源高效利用新基因挖掘与育种价值评价，2023-2025，主持（课题）；
4.国家自然科学基金（面上）：水稻苗期耐冷基因HAN2的克隆与功能机理分析，2021-2024，主持；
5.中国科学院青年创新促进会（会员）：茉莉酸调控水稻耐冷性的分子机制，2019-2022，主持；
6.湖南省重点研发计划（国际合作）：水稻淹涝适应性的遗传基础及其栽培轻简化应用，2020-2022，主持；
7.海南省崖州湾种子实验室（揭榜挂帅）：高温影响水稻分蘖形成的表观遗传机制，2021-2022，主持；
8.国家自然科学基金（面上）：水稻苗期耐冷基因qCTS11的克隆与功能分析，2014-2017，主持；
9.国家自然科学基金（青年）：东乡野生稻越冬耐寒性的遗传分析，2012-2014，主持；
10.中国科学院亚热带农业生态研究所青年前沿领域部署项目：水稻亚种间低温响应转录组学差异分析，2011-2012，主持。
1. Wu B, Meng J, Liu H, Mao D, Yin H, Zhang Z, Zhou X, Zhang B, Sherif A, Liu H, Li X, Xiao J, Yan W, Wang L, Li X, Chen W, Xie W, Yin P, Zhang Q, Xing Y. Suppressing a phosphohydrolase of cytokinin nucleotide enhances grain yield in rice. Nat Genet. 2023 Aug;55(8):1381-1389.
2. Mao D, Tao S, Li X, Gao D, Tang M, Liu C, Wu D, Bai L, He Z, Wang X, Yang L, Zhu Y, Zhang D, Zhang W, Chen C. The Harbinger transposon-derived gene PANDA epigenetically coordinates panicle number and grain size in rice. Plant Biotechnol J. 2022 Jun;20(6):1154-1166.
3.Mao D, Xin Y, Tan Y, Hu X, Bai J, Liu ZY, Yu Y, Li L, Peng C, Fan T, Zhu Y, Guo YL, Wang S, Lu D, Xing Y, Yuan L, Chen C. Natural variation in the HAN1 gene confers chilling tolerance in rice and allowed adaptation to a temperate climate. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3494-3501.
5. Mao D, Yu L, Chen D, Li L, Zhu Y, Xiao Y, Zhang D, Chen C. Multiple cold resistance loci confer the high cold tolerance adaptation of Dongxiang wild rice (Oryza rufipogon) to its high-latitude habitat. Theor Appl Genet. 2015 Jul;128(7):1359-71.
6. Liu T, Huang L, Liu P, Cui C, Chen C, Mao D. The RISE Method Based on Rare Allele Infusion and Sanger Sequencing Estimation: A Simple, Cheap, and Efficient Method for Detecting Transgenic Copy Number in Rice. Rice Science. DOI：10.1016/j.rsci.2024.05.001.
7. Liu T, Bai L, Huang L, Mao D. NP and 9311 are excellent population parents for screening QTLs of potassium-efficient rice. PLoS One. 2023 Apr 14;18(4):e0284510.
8. Li L, Mao D, Sun L, Wang R, Tan L, Zhu Y, Huang H, Peng C, Zhao Y, Wang J, Huang D, Chen C. CF1 reduces grain-cadmium levels in rice (Oryza sativa). Plant J. 2022 Jun;110(5):1305-1318.
9. Li X, Xiang F, Zhang W, Yan J, Li X, Zhong M, Yang P, Chen C, Liu X, Mao D, Zhao X. Characterization and fine mapping of a new dwarf mutant in Brassica napus. BMC Plant Biol. 2021 Feb 26;21(1):117.
10. Chen K, Peng Y, Zhang L, Wang L, Mao D, Zhao Z, Bai L, Wang L. Whole transcriptome analysis resulted in the identification of Chinese sprangletop (Leptochloa chinensis) genes involved in cyhalofop-butyl tolerance. BMC Genomics. 2021 Jul 9;22(1):521.
11. Tan Y, Sun L, Song Q, Mao D, Zhou J, Jiang Y, Wang J, Fan T, Zhu Q, Huang D, Xiao H, Chen C. Genetic architecture of subspecies divergence in trace mineral accumulation and elemental correlations in the rice grain. Theor Appl Genet. 2020 Feb;133(2):529-545.
12. Yu Y, Hu X, Zhu Y, Mao D (2020) Re-evaluation of the rice ‘Green Revolution’ gene: the weak allele SD1-EQ from japonica rice may be beneficial for super indica rice breeding in the post-Green Revolution era. Mol Breed. 40:84.
13. Li L, Chen H, Mao D (2019) Pyramiding of rapid germination loci from Oryza Sativa cultivar ‘Xeqingzao B’ and cold tolerance loci from Dongxiang wild rice to increase climate resilience of cultivated rice. Mol Breed. 39:85.
14. Li G, Jin J, Zhou Y, Bai X, Mao D, Tan C, Wang G, Ouyang Y. Genome-wide dissection of segregation distortion using multiple inter-subspecific crosses in rice. Sci China Life Sci. 2019 Apr;62(4):507-516.
15. Li L, Mao D (2018) Deployment of cold tolerance loci from Oryza sativa ssp. Japonica cv. ‘Nipponbare’ in a high-yielding Indica rice cultivar 93-11. Plant Breed. 137(4) 553-560.
16. Tang M, Zhou C, Meng L, Mao D, Peng C, Zhu Y, Huang D, Tan Z, Chen C, Liu C, Zhang D. Overexpression of OsSPL9 enhances accumulation of Cu in rice grain and improves its digestibility and metabolism. J Genet Genomics. 2016 Nov 20;43(11):673-676.
17. Bai X, Huang Y, Mao D, Wen M, Zhang L, Xing Y. Regulatory role of FZP in the determination of panicle branching and spikelet formation in rice. Sci Rep. 2016 Jan 8;6:19022.
18. Zhang L, Mao D, Xing F, Bai X, Zhao H, Yao W, Li G, Xie W, Xing Y. Loss of function of OsMADS3 via the insertion of a novel retrotransposon leads to recessive male sterility in rice (Oryza sativa). Plant Sci. 2015 Sep;238:188-97.
19. Wu B, Mao D, Liu T, Li Z, Xing Y (2015) Two quantitative trait loci for grain yield and plant height on chromosome 3 are tightly linked in coupling phase in rice. Mol Breeding. 35: 156.
20. Yao W, Sun L, Zhou H, Yang F, Mao D, Wang J, Chen L, Zhang G, Dai J, Xiao G, Chen C (2015) Additive, dominant parental effects control the inheritance of grain cadmium accumulation in hybrid rice. Mol Breeding. 35: 39.
21. Tang M, Mao D, Xu L, Li D, Song S, Chen C. Integrated analysis of miRNA and mRNA expression profiles in response to Cd exposure in rice seedlings. BMC Genomics. 2014 Oct 1;15(1):835.
22. Yang C, Li D, Mao D, Liu X, Ji C, Li X, Zhao X, Cheng Z, Chen C, Zhu L. Overexpression of microRNA319 impacts leaf morphogenesis and leads to enhanced cold tolerance in rice (Oryza sativa L.). Plant Cell Environ. 2013 Dec;36(12):2207-18.
23. Mao D, Chen C. Colinearity and similar expression pattern of rice DREB1s reveal their functional conservation in the cold-responsive pathway. PLoS One. 2012;7(10):e47275.
24. Mao D, Yu H, Liu T, Yang G, Xing Y. Two complementary recessive genes in duplicated segments control etiolation in rice. Theor Appl Genet. 2011 Feb;122(2):373-83.
25. Mao D, Liu T, Xu C, Li X, Xing Y (2011) Epistasis and complementary gene action adequately account for the genetic bases of transgressive segregation of kilo grain weight in rice. Euphytica. 180(2):261-271.
26. Liu T, Mao D, Zhang S, Xu C, Xing Y (2009) Fine mapping SPP1, a QTL controlling the number of spikelets per panicle, to a BAC clone in rice (Oryza sativa). Theor Appl Genet. 118(8):1509-17.
27. 何展坤,崔延春,徐庆国,毛东海.水稻果皮花青素含量的全基因组关联分析.农业现代化研究,2023,44(02):370-380.
28. 吴丹,毛东海,赵小英.植物低温响应的分子机制研究进展.生命科学研究,2022,26(01):67-75.
29. 胡潇婕,毛东海.基于RNA-Seq技术分析植物激素信号途径在水稻幼苗中对低温胁迫的应答规律.农业现代化研究,2019,40(05):878-890.
30. 姚文元,禹黎,陈大洲,肖叶青,孙亮,陈彩艳,毛东海.东乡野生稻的粒形相关QTL分析.杂交水稻,2014,(06),50-55.