博士，研究员，博士研究生导师。2005年在中国科学院遗传与发育生物学研究所获遗传学博士学位。2005.11-2009.08 在美国Plant & Science Department,University of Kentucky 从事博士后研究工作；2009年9月至今受聘于中国科学院亚热带农业生态研究所。自参加研究工作以来一直从事水稻（Oryza sativa）分子遗传学研究。目前的工作聚焦于水稻镉积累及微量矿质营养的遗传调控网络解析与低镉水稻分子设计育种。利用遗传群体、自然群体和突变体， 结合正向遗传学、反向遗传学以及基因组学等方法克隆水稻镉积累及微量矿质营养调控相关基因，构建其信号传递网络，筛选优异等位基因变异，培育低镉、优质、高产水稻新种质。

团队成员

孙  亮（副研）；朱玉兴（助研），谭龙涛（助研）；李兰英（助研）

博士研究生

陈于超；屈蒙蒙；韩裕轩；夏煜琪；胡衡量

硕士研究生

章鑫鑫；彭宇

课题组近五年来先后承担的课题包括：中国科学院“先导专项”（A）（子课题）1项，国家重点研发项目（课题）2项，自然科学基金区域合作重点项目2项。

Liu P.,Sun L.,Zhang Y.,Tan Y.,Zhu Y.,Peng C.,Wang J.,Yan H.,Mao D.,Liang G.,Liang G.,Li X.,Liang Y.,Wang F.,He Z.,Tang W.,Huang D., Chen C#. The metal tolerance protein OsMTP11 facilitates cadmium sequestration in the vacuoles of leaf vascular cells for restricting its translocation into rice grains. Mol Plant. 2024 Nov 4;17(11):1733-1752. doi: 10.1016/j.molp.2024.09.012.

Liu T.,Huang L.,Liu P.,Cui Y.,Chen C.,Mao D#. RISE Method Based on Rare Allele Infusion and Sanger Sequencing Estimation: A Simple,Cheap,and Efficient Method for Detecting Transgene Copy Number in Rice. Rice Science. 2024;31(5):499-502. Doi:10.1016/j.rsci.2024.05.001.

Sun L.,Tan Y.,Chen C#. The road toward Cd-safe rice: From mass selection to marker-assisted selection and genetic manipulation. The Crop Journal. 2023 August 2023;11(4):1059-1071. Doi:10.1016/j.cj.2023.01.007.

Liu T.,Hu W.,Weng L.,Deng L.,Li J.,Yu J.,Zhou Z.,Liu Y.,Chen C.,Teng S.,Zhao Z.,Xiao G#. Phenotypic and genetic dissection of the contents of important metallic elements in hybrid rice grown in cadmium-contaminated paddy fields. Heliyon. 2023 Sep 9;9(9):e19919. doi: 10.1016/j.heliyon.2023.e19919.

Li,L.,Mao,D.,Sun,L.,Wang,R.,Tan,L.,Zhu,Y.,Huang,H.,Peng,C.,Zhao,Y.,Wang,J.,Huang,D. and Chen,C#. CF1 reduces grain-Cd levels in rice (Oryza sativa). Plant J. 2022 Jun;110(5):1305-1318. doi: 10.1111/tpj.15736.

Mao,D*.,Tao,S*.,Li,X*.,Gao,D.,Tang,M.,Liu,C.,Wu,D.,Bai,L.,He,Z.,Wang,X.,Yang,L.,Zhu,Y.,Zhang,D#.,Zhang,W#. and Chen,C#. The Harbinger transposon-derived gene PANDA epigenetically coordinates panicle number and grain size in rice. Plant Biotechnol J. 2022 Jun;20(6):1154-1166. doi: 10.1111/pbi.13799.

Ma X,Feng Y,Yang Y,Li X,Shi Y,Tao S,Cheng X,Huang J,Wang XE,Chen C,Monchaud D,Zhang W#. Genome-wide characterization of i-motifs and their potential roles in the stability and evolution of transposable elements in rice. Nucleic Acids Res. 2022 Feb 21: gkac121. doi: 10.1093/nar/gkac121.

Sun L*,Wang R*,Tang W*,Chen Y*,Zhou J,Ma H,Li S,Deng H,Han L,Chen Y,Tan Y,Zhu Y,Lin D,Zhu Q,Wang J,Huang D,Chen C#. 2022. Robust identification of low-Cd rice varieties by boosting the genotypic effect of grain Cd accumulation in combination with marker-assisted selection. J Hazard Mater. 424(Pt D):127703. doi: 10.1016/j.jhazmat.2021.127703. Epub 2021 Nov 6. PMID: 34799159.

Zhou Z,Sun L,Hu W,Zhou B,Tao S,Zhang S,Lv Y,Zhao Z#,Chen C#.2021 Breeding High-Grain Quality and Blast Resistant Rice Variety Using Combination of Traditional Breeding and Marker-Assisted Selection. Rice Sci. 28 (5):422-426 DOI:10.1016/j.rsci.2021.07.002.

Feng Y,Tao S,Zhang P,Sperti FR,Liu G,Cheng X,Zhang T,Yu H,Wang XE,Chen C,Monchaud D,Zhang W#. 2022. Epigenomic features of DNA G-quadruplexes and their roles in regulating rice gene transcription. Plant Physiol. 188(3):1632-1648. doi: 10.1093/plphys/kiab566.

Tang L,Dong J,Tan L,Ji Z,Li Y,Sun Y, Chen C,Lv Q,Mao B,Hu Y,Zhao B#. 2021. Overexpression of OsLCT2,a Low-Affinity Cation Transporter Gene,Reduces Cadmium Accumulation in Shoots and Grains of Rice. Rice (N Y). 14(1):89. doi: 10.1186/s12284-021-00530-8.

Li X,Xiang F,Zhang W,Yan J,Li X,Zhong M,Yang P,Chen C,Liu X,Mao D,Zhao X. 2021. Characterization and fine mapping of a new dwarf mutant in Brassica napus. BMC Plant Biol. 21(1):117. doi: 10.1186/s12870-021-02885-y.

Liu T,Sun L,Meng Q,Yu J,Weng L,Li J,Deng L,Zhu Q,Gu X, Chen C,Teng S & Xiao,G. (2021). Phenotypic and genetic dissection of cadmium accumulation in roots,nodes and grains of rice hybrids. Plant and Soil,463(1),39-53. DOI: https://doi.org/10.1007/s11104-021-04877-1.

Tan L,Qu M,Zhu Y,Peng C,Wang J,Gao D & Chen C#. 2020. The OsZIP5 and OsZIP9 transporters function synergistically in Zn/Cd uptake in rice. Plant Physiol. 183(3):1235-1249. DOI: 10.1104/pp.19.01569.

Tan Y,Sun L,Song Q,Mao D,Zhou J,Jiang Y,Wang J,Fan T,Zhu Q,Huang D,Xiao H,Chen C#. 2020. Genetic architecture of subspecies divergence in trace mineral accumulation and elemental correlations in the rice grain. Theor Appl Genet. 133(2):529-545. doi: 10.1007/s00122-019-03485-z.

Fang Y*,Chen L*,Lin K,Feng Y,Zhang P,Pan X,Sanders J,Wu Y,Wang X,Su Z,Chen C,Wei H#,Zhang W#. 2019. Characterization of functional relationships of R-loops with gene transcription and epigenetic modifications in rice. Genome Res. 29(8):1287-1297. doi: 10.1101/gr.246009.118

Yan H*,Xu W*,Xie J*,Gao Y,Wu L,Sun L,Feng L,Chen X,Zhang T,Dai C,Li T,Lin X,Zhang Z,Wang X,Li F,Zhu X,Li J,Li Z,Chen C,Ma M,Zhang H#,He Z#. 2019. Variation of a major facilitator superfamily gene contributes to differential cadmium accumulation between rice subspecies. Nat Commun. 10(1):2562. doi: 10.1038/s41467-019-10544-y.

Tan L,Zhu Y,Fan T,Peng C,Wang J,Sun L#,Chen C. 2019. OsZIP7 functions in xylem loading in roots and inter-vascular transfer in nodes to deliver Zn/Cd to grain in rice. Biochem Biophys Res Commun. 512(1):112-118. doi: 10.1016/j.bbrc.2019.03.024.

Mao D*,Xin Y*,Tan Y,Hu X,Bai J,Liu ZY,Yu Y,Li L,Peng C,Fan T,Zhu Y,Guo YL,Wang S,Lu D,Xing Y,Yuan L#,Chen C#. 2019. Natural variation in the HAN1gene confers chilling tolerance in rice and allowed adaptation to a temperate climate.Proc Natl Acad Sci U S A. 116(9):3494-3501. doi: 10.1073/pnas.1819769116.

Tang L,Mao B,Li Y,Lv Q,Zhang L,Chen C,He H,Wang W,Zeng X,Shao Y,Pan Y,Hu Y,Peng Y,Fu X,Li H#,Xia S#,Zhao B#. 2017. Knockout of OsNramp5 using the CRISPR/Cas9 system produces low Cd-accumulating indica rice without compromising yield. Sci Rep. 7(1):14438. doi: 10.1038/s41598-017-14832-9.

Tang,M.,Zhou,C.,Meng,L.,Mao,D.,Liu,C.,Peng,C.,Zhu,Y.,Zhang,D.,Huang,D.,Tan,Z.,Chen,C^#. 2016. Overexpression of OsSPL9 enhances accumulation of Cu in rice grain and improves its digestibility and metabolism,Journal of Genetics and Genomics. 43(11):673. DOI: 10.1016/j.jgg.2016.09.004.

Li D*,Huang Z*,Song S*^#,Xin Y*^#,Mao D*,Lv Q*,Zhou M,Tian D,Tang M,Wu Q,Liu X,Chen T,Song X,Fu X,Zhao B,Liang C,Li A,Liu G,Li S,Hu S,Cao X,Yu J,Yuan L^#,Chen C^#,Zhu L^#. 2016. Integrated analysis of phenome,genome,and transcriptome of hybrid rice uncovered multiple heterosis-related loci for yield increase. Proc Natl Acad Sci USA. 113(41):E6026–E6035. DOI: 10.1073/pnas.1610115113.

Sun L,Xu X,Jiang Y,Zhu Q,Yang F,Zhou J,Yang Y,Huang Z,Li A,Chen L,Tang W,Zhang G,Wang J,Xiao G,Huang D, Chen C^#. 2016. Genetic Diversity,Rather than Cultivar Type,Determines Relative Grain Cd Accumulation in Hybrid Rice. Front Plant Sci. 7:1407. DOI:10.3389/fpls.2016.01407.

Mao D*,Yu L*,Chen D,Li L,Zhu Y,Xiao Y,Zhang D, Chen C^#. 2015. Multiple cold resistance loci confer the high cold tolerance adaptation of Dongxiang wild rice (Oryza rufipogon) to its high-latitude habitat. Theor Appl Genet. 128:1359–1371. DOI: 10.1007/s00122-015-2511-3.

Liu L*,He X*,Wang K,Xie Y,Xie Q,O'Donnell A,Chen C^#. 2015. The Bradyrhizobium-legume symbiosis is dominant in the shrubby ecosystem of the Karst region,Southwest China. European Journal of Soil Biology. 68: 1-8. DOI:10.1016/j.ejsobi.2015.02.004.

Hu Y,Wu S,Sun Y,Li T,Zhang X, Chen C,Lin G,Chen B. 2015. Arbuscular mycorrhizal symbiosis can mitigate the negative effects of night warming on physiological traits of Medicago truncatula L. Mycorrhiza. 25(2):131-42. DOI: 10.1007/s00572-014-0595-2.

Yao W*,Sun L *,Zhou Hao,Yang Fei,Mao D,Wang J,Chen L,Zhang G,Dai J,Xiao G& Chen C^#. 2015. Additive,dominant parental effects control the inheritance of grain cadmium accumulation in hybrid rice. Molecular Breeding. 35:39. DOI: 10.1007/s11032-015-0246-0.

Tang M*，Mao D*，Xu L，Li D，Song S， Chen C ^#. 2014. Integrated analysis of miRNA and mRNA expression profiles in response to Cd exposure in rice seedlings. BMC Genomics. 15: 835. DOI: 10.1186/1471-2164-15-835..

Yang C*,Li D*,Liu X,Ji C,Hao L,Zhao X,Li X,Chen C,Cheng Z,Zhu L. 2014. OsMYB103L,an R2R3-MYB transcription factor,influences leaf rolling and mechanical strength in rice (Oryza sativa L.). BMC Plant Biol. 14:158. DOI: 10.1186/1471-2229-14-158.

Liu W,Zhang D^#,Tang M,Li D,Zhu Y,Zhu L, Chen C^#.  2013. THIS1 is a putative lipase that regulates tillering,plant height and spikelet fertility in rice. J EXP BOT. 64（14）：4389-402. DOI: 10.1093/jxb/ert256.

Yang C*,Li D*,Mao D,Liu X,Ji C,Li X,Zhao X,Cheng Z,Chen C,Zhu L. 2013. Overexpression of microRNA319 impacts leaf morphogenesis and leads to enhanced cold tolerance in rice (Oryza sativa L.). Plant Cell Environ. 36(12):2207-18. DOI: 10.1111/pce. 12130.

Chen C,Zhu H. 2013. Are common symbiosis genes required for endophytic rice-rhizobial interactions?  Plant Signaling & Behavior. 8:e25453. DOI: 10.4161/psb.25453.

Yuan H,Ge T,Chen C,O'Donnell AG,Wu J. 2012. Significant role for microbial autotrophy in the sequestration of soil carbon. Appl Environ Microbiol. 78(7):2328-36. DOI: 10.1128/AEM.06881-11.

Mao D,Chen C^#. 2012. Colinearity and similar expression pattern of rice DREB1s reveal their functional conservation in the cold-responsive pathway. PLoS ONE. 7(10):e47275. doi: 10.1371/journal.pone.0047275.

Wang A,Tang J,Li D,Chen C,Zhao X,Zhu L. 2009. Isolation and functional analysis of LiYAB1,a YABBY family gene,from lily (Lilium longiflorum). J Plant Physiol. 166(9):988-95. DOI:10.1016/j.jplph.2008.11.011.

Chen C,Zou J,Zhang S,Zaitlin D,Zhu L. 2009. Strigolactones are a newly-defined class of plant hormones that inhibit shoot branching and mediate the interaction of plant-AM fungi and plant-parasitic weeds. Sci China C Life Sci. 52: 693-700. DOI: 10.1007/s11427-009-0104-6.

Chen C,Fan C,Gao M,Zhu H. 2009. Antiquity of CASTOR and POLLUX,the twin ion channel-encoding genes key to the evolution of root symbiosis in plants. Plant Physiol. 149:306-17. Doi: 10.1104/pp.108.131540.

Chen C,Ané,J,Zhu H. 2008. OsIPD3,an ortholog of the medicago truncatula DMI3 interacting protein IPD3,is required for mycorrhizal symbiosis in rice. New Phytologist. 180(2):311-15. DOI: 10.1111/j.1469-8137.2008.02612.x.

Chen C,Gao M,Liu J,Zhu H. 2007. Fungal symbiosis in rice requires an ortholog of a legume common symbiosis gene encoding a Ca2+/calmodulin-dependent protein kinase. Plant Physiol. 145(4):1619-28. DOI:10.1104/pp.107.109876.

Chen C*,Xiao H*,Zhang W,Wang A,Xia Z,Li X,Zhai W,Cheng Z,Zhu L. 2006. Adapting rice anther culture to gene transformation and RNA interference. Sci China C Life Sci. 49 (5):414-28. DOI: 10.1007/s11427-006-2013-2.

Zhai W,Chen C,Zhu X,Chen X,Zhang D,Li X,Zhu L. 2004. Analysis of T-DNA- Xa21 loci and bacterial blight resistance effects of the transgene Xa21 in transgenic rice. Theor Appl Genet. 109(3):534-42. DOI: 10.1007/s00122-004-1670-4.

*:these authors contributed equally. ^#:Author for correspondence.

新品种权

陈彩艳;唐文帮;丁新材;孙亮,望恢441 （CNA20161437.9）,中国  

陈彩艳;唐文帮;丁新才;孙亮,望恢1013 （CNA20161438.8）,中国

审定品种（合作）

艳两优039（湘审稻20200015）；

麓山思苗（湘审稻20200037）；

枫林思苗（湘审稻20200038）；

T两优131（湘审稻20200040）；

望两优889（湘审稻20180039）；

艳66S（安徽省鉴定）